Total Hip Replacement (THR)
Patient Selection, Fixation Systems & Clinical Outcomes
Pathophysiology of Coxofemoral OA
Hip dysplasia is characterized by abnormal development and varying degrees of coxofemoral joint laxity. This laxity leads to subluxation, resulting in abnormal wear on the articular cartilage, microfractures of the subchondral bone, and eventual severe osteoarthritis (OA). While the onset of clinical signs does not always occur bilaterally simultaneously, dysplasia is almost universally a bilateral condition.
Clinical presentation ranges from subtle gait alterations (e.g., "bunny hopping" at a run) and reluctance to climb stairs, to severe hindlimb lameness and muscle atrophy. Total Hip Replacement (THR) remains the definitive surgical intervention, designed to restore the normal anatomical centre of rotation and provide lifelong, pain-free mobility.
Fixation Systems: CFX, BFX & KYON
Since the first canine THR in 1957, implant technology has advanced exponentially. BioMedtrix introduced the CFX® (Cemented Fixation) system in 1990 and the BFX® (Biologic Fixation) in 2003. To date, over 37,550 procedures have been performed using these implants on patients ranging from 1.5 kg to 80 kg, including felines. Modern veterinary surgeons typically select between cemented and cementless systems based on patient morphology.
Cemented Fixation (CFX)
Utilizes polymethylmethacrylate (PMMA) bone cement to mechanically interlock the implants with the trabecular bone.
- Indications: Older patients, "stove-pipe" femoral morphologies (low Canal Flare Index), or poor bone stock.
- Advantage: Immediate stabilization upon cement curing.
- Risk: Aseptic loosening over time due to cement mantle fatigue; highly susceptible to catastrophic failure if biofilm forms on the PMMA.
Biologic Fixation (BFX / KYON)
Utilizes porous-coated titanium or specialized screw-in/press-fit components to promote osteointegration (bone ingrowth).
- Indications: Younger, highly active dogs with healthy bone stock and a high Canal Flare Index.
- Advantage: Eliminates the risk of cement-mantle degradation. Implants become permanently integrated into the skeleton.
- Risk: Requires flawless initial press-fit stability. Risk of early subsidence or diaphyseal fracture before osteointegration completes (first 4-6 weeks).
Pre-operative Templating & Sizing
Successful THR relies heavily on meticulous pre-operative planning. Using calibrated digital radiographs and CAD templating software, the surgeon accurately determines the appropriate size for the femoral stem, femoral head, and acetabular cup.
During templating, the surgeon assesses the Canal Flare Index (CFI) to decide between cemented or cementless stems, ensuring the implant achieves an adequate cortical index (fill). For the acetabulum, the goal is to select a cup size that maximizes coverage while preserving the medial subchondral bone to prevent intrapelvic protrusion.
The Hip vs. Stifle (CCL) Dilemma
A classic diagnostic trap in veterinary orthopaedics is the large-breed dog presenting with hindlimb lameness and dramatic radiographic evidence of hip dysplasia. Studies indicate that up to 30% of dogs referred for hip dysplasia actually suffer from cranial cruciate ligament (CCL) rupture as the primary cause of their acute lameness.
Staging THR and Leveling Osteotomies (TPLO / CBLO)
Dogs must be carefully evaluated for concurrent stifle disease (via cranial drawer and tibial compression tests) before a THR is performed. If a patient requires surgery for both conditions on the same limb, the stifle is almost always prioritized.
- Dynamic Stability First: Performing a TPLO or CBLO restores the dynamic weight-bearing capacity of the limb. Subjecting a cruciate-deficient stifle to the demanding rehabilitation of a THR significantly increases the risk of post-THR luxation or implant failure due to poor limb use.
- Wait Times: A THR should be delayed until the leveling osteotomy (TPLO/CBLO) has achieved complete radiographic union and the patient has regained appropriate muscle mass to support the new hip joint.
Biomechanical Superiority over FHO
For dogs with severe hip dysplasia, the primary surgical alternative to a THR is a Femoral Head Ostectomy (FHO). An FHO is a salvage procedure that removes the femoral head and neck, relying on scar tissue to form a pseudoarthrosis (false joint). While an FHO eliminates bone-on-bone contact, it severely alters the biomechanics of the hip joint, resulting in limb shortening and permanent gait alterations.
Clinical Outcomes: Pain relief following THR is significantly more predictable than after FHO. Objective kinematic research using force plate analysis demonstrates that dogs return to normal Peak Vertical Force (PVF) within three to six months following THR. FHO outcomes are less predictable, particularly in dogs over 20 kg, and patients often require long-term NSAID therapy. THR eliminates the need for chronic drug therapy, mitigating the risks of long-term gastrointestinal or renal complications.
Complication Profiles & Recovery
The success rate for THR is remarkably high (routinely cited at >90-95%), and the implants are designed to last the patient's lifetime. However, it is a technically demanding procedure with a known complication profile. Total complication rates hover around 5-10%.
- Luxation: The most common early complication, usually occurring in a craniodorsal direction due to inadequate muscle mass, poor implant version/angle, or failure to restrict post-operative activity.
- Femoral Fracture: Fissures can occur during broaching of the femur or post-operatively (subsidence) before biologic integration is complete.
- Infection: A devastating complication requiring implant removal. Meticulous sterile technique and prophylactic antibiotics are critical.
- Neuropraxia: Transient sciatic nerve injury can occur due to retraction during surgery but typically resolves within several weeks.
Patients are typically hospitalized for 1-3 days. While they often begin weight-bearing within 24 hours, strict leash restriction and supervised rehabilitation are mandatory for 6-8 weeks to allow for soft tissue healing and, in the case of BFX systems, initial osteointegration.
Surgical Technique Videos
KYON THR: Breakthroughs & Biologic Fixation
BioMedtrix Universal Hip System: 3D Animation
Selected Literature & References
- Liska, W.D. (2010). "Micro total hip replacement in dogs and cats." Veterinary Surgery.
- Powers, M.Y., et al. (2005). "Prevalence of cranial cruciate ligament rupture in a population of dogs with lameness previously attributed to hip dysplasia: 369 cases." JAVMA.
- Off, W., & Matis, U. (2010). "Excision arthroplasty of the hip joint in dogs and cats. Clinical, radiographic, and gait analysis findings." Vet Comp Orthop Traumatol.